Maybe the first real dry powdered inhaler was patented in 1864 by Alfred E. Newman. Â After correspondence with Dr. James in New York, he put together an inhaler that was designed after a mantle clock “with an orifice at one side, inside was a mesh and a crank shaft with feather beaters. Powder was placed into the bottom of the box and the patient would put their mouth to the orifice and inhale while the handle was cranked causing the feathers to beat the powder creating a dust, which would pass through the mesh toward the mouth.”
Newman realized the powder must be “pulverized” and that it “must be kept dry,” and this is a similar concept to modern dry powder inhalers. Â The Newton device was designed for potassium chlorate, and it was mainly designed for diseases of the throat. Yet still it was a revolutionary concept. Â (1)
According to Mark Sanders, it was also used for tuberculosis. Â (2)
Assuming my links hold up, you can see a picture of this inhaler both here and here.
References:
- Smyth, Hugh D.C., Anthony J. Hickey, editors, “Controlled Pulmonary Delivery,” 2011, New York, Springer, page 60-61
- Sanders, Mark, “Pioneers of Inhalation: Vapour Trails and Powder Monkey,” from Inhalatorium.com: Online Museum of inhaler technology, slide show presentation, accessed on 11/13/12
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